Cognitive Flexibility Theory was founded by Dr. Spiro along with Paul Feltovich and Richard Coulson. They deal with applying this knowledge to new approaches while designing hypermedia. His research includes knowledge acquisition in complex domains, hypermedia learning environments, multimedia case-based methods in professional education, biomedical cognition, and constructive processes in comprehension and recall (WCER, 2004). Most of his research deals with trying to find out ways to avoid over simplifying of instructions while designing them.

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